Other Information: Do not use if printed sealed pouch is torn, open or incompletely sealed. Do not use if seal over tube opening has been punctured. Do not purchase if carton is open. Store at 20 degrees - 25 degrees C (68 degrees - 77 degrees F). This is a 1-dose treatment. Most women do not get complete relief of their symptoms in just 1 day. Most women get some improvement in 1 day and complete relief by 7 days. Ovule insert + plus external cream for itch relief. Stays in place. Clinically proven. Stays in place. Cures most vaginal yeast infections. Relieves associated external itching and irritation. www.Monistat.com. Questions? If you have any questions or comments, please call 1-877-666-4782 or visit our website www.monistat.com. If you have any or comments, please call 1-877-Monistat (1-877-666-4782) or visit our website at www.Monistat.com.